Two main types of assistance are  available from pharmaceutical companies. Several companies offer programs that  allow consumers to take a discount drug card to the pharmacy to get a discount  off of the price of prescription drugs. And most major pharmaceutical companies  offer PAPs, which give free or low-cost medicines to people in need.
              Because these programs typically  target people without health insurance and people who don't qualify for  government-funded programs, some are expected to change over the coming year  with the launch of the Medicare Prescription Drug Benefit. For example, as of  June 2005, GlaxoSmithKline (GSK) had about 200,000 members in its Orange Card  program, according to Patty Seif, a spokeswoman for GSK. The card offers 20  percent to 40 percent off the usual price of the company's drugs, and is open  to older people who are without health insurance and who have an annual income  not exceeding $30,000 to $40,000 for a couple. As a program for Medicare  enrollees, the Orange Card program's final year will be 2006, Seif says.
              The Together Rx Card, launched  by 10 pharmaceutical companies, provides financial help on prescription drugs  until the Medicare drug benefit starts. The card gives U.S. residents  who don't have drug coverage and who are within certain income levels average  savings of 25 percent to 40 percent on their prescription drugs. The final day  to use a Together Rx Card is Dec. 31, 2005.
              Maggie Kohn, a spokeswoman for  the drug manufacturer Merck, says that unlike many other programs, Merck's  discount program offers discounts of 15 percent to 40 percent on many of the  company's medicines to uninsured patients, regardless of age or income. About  15,000 people signed up for the program within the first few weeks that it  began in April 2005, Kohn says.
              Merck's PAP supplied 700,000  patients with 6.7 million prescriptions valued at $490 million in 2004, Kohn  says. Patients may qualify if they have a household income below $19,140 for  individuals, $25,660 for couples, and $38,700 for a family of four. "We do  sometimes make exceptions for patients whose incomes exceed these amounts in  special circumstances like if they are taking a number of medicines," Kohn  says.
              The Partnership for Prescription  Assistance (PPA), which was launched in April 2005, is an industry initiative  that's helping patients find assistance programs faster. "With one call,"  Seif says, "patients are directed to programs that could be most  helpful." The PPA provides a single point of access to more than 275  public and private PAPs, including more than 150 programs offered by drug  companies. The PPA also will show people how to contact Medicare and other  government programs.
  "We know that medicines,  when taken as prescribed, improve lives and decrease overall health care  spending," Seif says. "But for people who can't pay for them, any  price is too high. That's why GSK and the pharmaceutical industry support  programs that make our programs accessible." In 2004, GSK provided 372.5  million dollars' worth of free medicine.
              Every company has its own  eligibility criteria for PAPs, and, in most cases, U.S. citizenship and some proof of  income, such as tax records or a record of social security benefits, are  required.
              In the April 1, 2005, issue of  the American Journal of Health-System  Pharmacy, researchers looked at clinics' use and assessment of  PAPs. They concluded that PAPs help fill a major gap in health insurance  coverage, but that consistent eligibility and application procedures are  needed. The researchers identified the program's responses and changes to the  Medicare drug benefit as a potential area of study.
              They also reported that the  benefits of helping patients get needed medication came with additional costs  of clinic time spent dealing with them. Lisa McTavish, M.D., a family physician  with the Arnett Clinic in Rossville,   Ind., says her small office  couldn't afford to help patients navigate PAPs until 2003, when a volunteer  patient advocate named Susie Gray came on board. McTavish says it's been worth  it. In the first six months of 2005, Gray helped patients save about $63,000  through PAPs.
  "We have found that  hospital and emergency admissions have decreased for most patients in the  program," McTavish says. "That's because the patients are taking the  medications they need and they aren't as stressed about how they will pay for  them."
              Gray, who works as a patient  advocate two days a week, says she started with 13 patients in 2003 and now  works with about 130. "I start by finding out which company makes the  particular medication, then I get the forms and work with patients to fill them  out," Gray says. "It takes about four to eight weeks to hear back  about whether the patient is accepted." Gray also keeps track of  medication orders and re-orders.
              Patients who don't have access  to someone like Gray can initiate the PAP process on their own by printing  forms off the Internet or by calling pharmaceutical companies directly to  request forms. Patients should fill out as much as possible, and then take the  form to their doctor's office. PAP forms require a doctor's signature.
  "At first, many of the  patients who come to see me say they don't want the medication because they  can't afford it, so I help them realize what their options are," says  Gray, who decided to work as a patient advocate after helping her husband  through three heart attacks. "I feel good about what I'm doing," Gray  says. "A prescription doesn't do the patients any good if they can't get  the medicine."